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Metabolic Peptides

MariTide (Maridebart Cafraglutide) 2026: Amgen's Once-Monthly GLP-1/GIP Antagonist — Phase 2 Data & Phase 3 Status

Michael Court
September 22, 2026
7 min read

MariTide takes the opposite approach to tirzepatide: GLP-1 agonism plus GIP antagonism, delivered monthly via an antibody-peptide conjugate. Here's the Phase 2 NEJM data, safety profile, and where Amgen's Phase 3 MARITIME program stands in 2026.