Same-day dispatch
Order before 2pm ET — ships from Toronto
COA in every box
Batch-matched third-party certificate
Cold-pack shipped
Temperature-controlled packaging
Purity guarantee
Below spec? Replaced or refunded
GHK-Cu
The Gold Standard of Skin & Regenerative Research Peptides
GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. It is one of the most studied peptides in dermatological and regenerative research, with over 50 years of published research. Studies have investigated its role in collagen synthesis stimulation, wound repair, anti-inflammatory signaling, and gene expression modulation affecting over 4,000 human genes.
- Naturally occurring copper tripeptide with 50+ years of published research
- Among the most-studied compounds in dermatological and skin-repair literature
- Highest verified purity in our catalog at 99.5% HPLC
Vial size
50mg per vial · Lyophilized Powder · Ships same business day from Toronto
Questions about this batch? Text an agent at (905) 993-4764
99.5%
HPLC purity
Highest-purity batch in the Trinity catalog
70%
Plasma decline by age 60
GHK levels fall from ~200 ng/mL at age 20
4,000+
Genes modulated
Human gene-expression profiling of GHK-Cu
Research benefits
Collagen Synthesis
Stimulates collagen and glycosaminoglycan production in skin fibroblasts
Anti-Aging Signaling
Researched for reversing age-related gene expression changes
Wound Healing
Studied for accelerated skin repair, remodeling, and angiogenesis
Study findings
Summaries of published research on this compound. Findings are reported for scientific context only and do not constitute claims about this product.
Gene expression profiling
GHK was found to modulate expression of more than 4,000 human genes, broadly resetting profiles toward a healthier state in cell-culture models.
BioMed Research International · 2014
Collagen and glycosaminoglycan synthesis
GHK-Cu stimulated collagen, elastin, decorin and glycosaminoglycan production in fibroblast cultures and in vivo rodent skin models.
Connective Tissue Research · 1985
Facial skin study
A 12-week GHK-Cu topical protocol improved skin density, thickness and visible fine lines versus vehicle control in a controlled trial.
Journal of Cosmetic Dermatology · 2015
Wound healing acceleration
GHK-Cu accelerated wound contraction and increased angiogenesis in diabetic and ischemic wound models.
The FASEB Journal · 1988
What researchers report
Aggregated, anonymized observations from laboratories ordering this compound. Anecdotal and non-clinical.
The most-requested compound for topical formulation research in our order data.
Researchers frequently report the characteristic deep blue solution as an immediate visual confirmation of correct copper complexation.
Commonly paired with glutathione in brightening and anti-oxidative study designs.
Technical specifications
| Form | Lyophilized Powder |
| Sequence | Gly-His-Lys (Cu²⁺ complex) |
| Molecular Weight | 340.38 g/mol |
| Purity | ≥99% |
| Amount | 50mg per vial |
| Storage | Store at -20°C, protect from light |
| Shelf Life | 36 months (stored at -20°C) |
| COA | COA Available → View Lab Results |
Storage & reconstitution
Store lyophilized vial at -20°C, protected from light.
Reconstitute with sterile or bacteriostatic water — solution should be deep blue and clear.
Avoid contact with reducing agents which can destabilize the copper complex.
Research background
GHK was first identified in 1973 as a plasma factor that caused old liver tissue to behave like young tissue in research models.
The copper-bound form (GHK-Cu) has been the subject of 50+ years of dermatological and regenerative research.
Modern transcriptomic research has shown GHK-Cu modulates expression of over 4,000 human genes, many associated with aging and tissue repair.
Frequently stacked with
Glow Stack
GHK-Cu + BPC-157 + TB-500 — Trinity's signature skin, repair & regeneration stack.
COA AvailableThird-party verified
ISO 17025 accredited lab — Batch TR-GHKCU-2026-001
HPLC Purity
99.5%
Molecular Weight
✓ Verified
Endotoxin (LAL)
<0.5 EU/mg
Heavy Metals (ICP-MS)
✓ Pass
GHK-Cu — frequently asked
Why is the solution blue?
The blue colour comes from the copper(II) ion bound in the GHK tripeptide complex — it's a direct visual indicator of correct complexation.
How much published research exists?
GHK-Cu has been studied since 1973, with hundreds of peer-reviewed papers spanning wound healing, dermatology and gene expression.
What's it most often stacked with?
Glutathione, in skin brightening and oxidative-stress research designs.
How fast does it ship?
Orders placed before 2pm ET ship the same business day from Toronto with tracked Canada-wide delivery, typically arriving in 1–3 business days. Cold-pack packaging is used on every shipment.
What if the purity doesn't match the COA?
Every batch is HPLC and mass-spec verified by an ISO 17025 accredited third-party lab, and the batch-matched COA ships with your order. If an independent test comes back below the stated purity, we replace the order or refund it in full.
Is this legal to purchase in Canada?
Yes — these compounds are sold strictly as in-vitro research chemicals for laboratory use. They are not for human or veterinary use, and it is the purchaser's responsibility to comply with applicable federal and provincial regulations.
Ready to add GHK-Cu to your research?
≥99% HPLC-verified, endotoxin and heavy metals tested, batch-matched COA included. Ships same business day from Toronto.
Research Use Only Disclaimer
This product is sold exclusively for in-vitro research and laboratory use only. It is NOT intended for human or veterinary use, consumption, injection, or any clinical application. This product has not been evaluated by Health Canada, the FDA, or any other regulatory authority for safety or efficacy in humans or animals. Trinity makes no medical claims regarding this compound. Researchers must comply with all applicable federal, provincial/state, and local laws regarding the purchase, storage, and use of research compounds. By purchasing this product, you confirm you are a qualified researcher or licensed professional acting within the bounds of applicable law.